Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5874694 | 0.90 | FFAR3 (0.47) | TP53CA2CYP2D6CYP2C19POLB | |
| Oxalic Acid SCHEMBL5875009 | 0.90 | TP53 (0.44) | TP53CYP2D6CYP2C19POLBALDH1A1 | |
| Lactic Acid SCHEMBL21219127 | 0.87 | TP53 (0.69) | TP53CYP2D6CYP2C19POLBALDH1A1 | |
| SCHEMBL37338 | 0.84 | ALDH1A1 (0.46) | TP53ALDH1A1TSHRLMNA | |
| Cadaverine Tartrate SCHEMBL5874851 | 0.84 | TSHR (0.59) | TP53CYP2C19POLBALDH1A1TSHR | |
| Methylmalonic Acid SCHEMBL5874121 | 0.84 | TP53 (0.47) | TP53CYP2D6CYP2C19POLBALDH1A1 | |
| Malonic Acid SCHEMBL4864852 | 0.84 | LDHA (0.53) | TP53CYP2D6CYP2C19ALDH1A1LMNA | |
| Succinic Acid SCHEMBL5874469 | 0.82 | EGLN1 (0.50) | ALDH1A1LMNAFFAR3 | |
| Maleic Acid SCHEMBL9585170 | 0.82 | ALDH1A1 (0.52) | TP53POLBALDH1A1TSHRGAA | |
| Dichloroacetic Acid SCHEMBL5874749 | 0.82 | LMNA (0.56) | TP53POLBALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240138403-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2024-05-02 | — | — | US | claimed |
| US-20230021295-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2023-01-19 | — | — | US | claimed |
| WO-2023278670-A1 | SYNERGISTIC COMBINATIONS FOR REDUCING VOLATILITY OF AUXIN HERBICIDES | ETHOX CHEMICALS, LLC (US) | 2023-01-05 | — | — | WO | claimed |
| US-20240138403-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2024-05-02 | — | — | US | disclosed |
| US-20230021295-A1 | Synergistic Combinations for Reducing Volatility of Auxin Herbicides | ETHOX CHEMICALS, LLC | 2023-01-19 | — | — | US | disclosed |
| WO-2023278670-A1 | SYNERGISTIC COMBINATIONS FOR REDUCING VOLATILITY OF AUXIN HERBICIDES | ETHOX CHEMICALS, LLC (US) | 2023-01-05 | — | — | WO | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4844744-A | Liquid, phosphate-free single phase degreasing compositions | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0314750-A1 | COMPOSITION AND PROCESS FOR CLEANING OF FIRE-SIDE PARTS OF FIRING DEVICES | SCHAMSCHULA, György (HU) | 1989-05-10 | — | — | EP | disclosed |
| WO-1988009368-A1 | COMPOSITION AND PROCESS FOR CLEANING OF FIRE-SIDE PARTS OF FIRING DEVICES | SCHAMSCHULA GYOERGY (HU) | 1988-12-01 | — | — | WO | disclosed |
| EP-0008141-A1 | Detergent composition containing mixture of anionic sulfate and sulfonate surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |