Quinoline

Quinoline

SCHEMBL5874375

CC(C(=O)O)C(=O)O.c1ccc2ncccc2c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
NPSR1 Q6W5P4 2/20 0.47
RXFP1 Q9HBX9 2/20 0.47
KDM4E B2RXH2 2/20 0.47
PRNP P04156 1/20 0.47
MAPK10 P53779 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 1/20 0.46
AKR1C3 P42330 1/20 0.45
AKR1C2 P52895 1/20 0.45
PABPC1 P11940 1/20 0.44
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.44
PLK1 P53350 1/20 0.44
MAPT P10636 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL5874361 1.00 ALDH1A1 (0.61) ALDH1A1NPSR1RXFP1KDM4EPRNP
Quinoline SCHEMBL27820159 0.89 ALDH1A1 (0.61) ALDH1A1NPSR1RXFP1KDM4EPRNP
Quinoline SCHEMBL7081987 0.88 ALDH1A1 (0.59) ALDH1A1NPSR1RXFP1KDM4EPRNP
Quinoline SCHEMBL7081988 0.88 ALDH1A1 (0.59) ALDH1A1NPSR1RXFP1KDM4EPRNP
Quinoline SCHEMBL27303537 0.85 ALDH1A1 (0.71) ALDH1A1KDM4ESMN1; SMN2LMNAPABPC1
Quinoline SCHEMBL1783847 0.85 ALDH1A1 (0.71) ALDH1A1KDM4ESMN1; SMN2LMNAPABPC1
Quinoline SCHEMBL4747553 0.85 ALDH1A1 (0.55) ALDH1A1NPSR1RXFP1KDM4EPRNP
Quinoline SCHEMBL5874493 0.85 ALDH1A1 (0.77) ALDH1A1KDM4ESMN1; SMN2LMNAPABPC1
Quinoline SCHEMBL372690 0.85 ALDH1A1 (0.77) ALDH1A1KDM4ESMN1; SMN2LMNAPABPC1
Quinoline SCHEMBL5283313 0.85 ALDH1A1 (0.77) ALDH1A1KDM4ESMN1; SMN2LMNAPABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed