Glutarate

Glutarate

SCHEMBL5874673

C1CCNCC1.O=C(O)CCCC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.55
LMNA P02545 3/20 0.48
TSHR P16473 3/20 0.46
NFKB1 P19838 2/20 0.46
PMP22 Q01453 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 2/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ITGB3 P05106 2/20 0.42
ITGA2B P08514 2/20 0.42
CAMK2A Q9UQM7 1/20 0.42
GABRR3 A8MPY1 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
HDAC3 O15379 1/20 0.40
GABBR2 O75899 1/20 0.40
THRB P10828 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL5874662 1.00 SLC22A6 (0.55) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL5874403 0.95 LMNA (0.55) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL16670398 0.95 LMNA (0.55) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL336949 0.95 LMNA (0.55) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL5874393 0.95 LMNA (0.55) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL2293630 0.93 LMNA (0.52) SLC22A6LMNATSHRNFKB1PMP22
Sebacic Acid SCHEMBL11610099 0.93 TSHR (0.57) SLC22A6LMNATSHRNFKB1PMP22
Sebacic Acid SCHEMBL5875002 0.93 TSHR (0.57) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL18091137 0.93 LMNA (0.52) SLC22A6LMNATSHRNFKB1PMP22
Sebacic Acid SCHEMBL5874996 0.93 TSHR (0.57) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed