Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.72 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL8072838 | 0.97 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL9351884 | 0.97 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL3395553 | 0.93 | FFAR3 (0.62) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL10880700 | 0.91 | FFAR3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL2014131 | 0.89 | FFAR3 (0.56) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL5874535 | 0.88 | EGLN1 (0.56) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL27703264 | 0.88 | EGLN1 (0.56) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL5874529 | 0.88 | EGLN1 (0.56) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL339305 | 0.85 | FFAR3 (1.00) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL4446516 | 0.85 | FFAR3 (1.00) | HDAC3HDAC1HDAC2HDAC8FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418825-A | Method for purifying lipstatin | UNIV PEKING FOUNDER GROUP CO | 2015-03-18 | — | — | CN | claimed |
| US-20250242275-A1 | APPARATUS AND METHOD FOR PROCESSING A BIOMASS MATERIAL | BUSS-SMS-CANZLER GMBH (DE) | 2025-07-31 | — | — | US | disclosed |
| US-20250145889-A1 | METHOD FOR PROCESSING A BIOMASS MATERIAL | PROIONIC GMBH (AT) | 2025-05-08 | — | — | US | disclosed |
| CN-118804981-A | Method for processing biomass material | 普罗奥尼克股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| EP-4377467-A2 | METHOD FOR PROCESSING A BIOMASS MATERIAL | proionic GmbH (AT) | 2024-06-05 | — | — | EP | disclosed |
| CN-114477249-B | Method for preparing high-purity magnesium hydroxide and calcium sulfate by adopting calcium carbide furnace purification ash | 龙岩紫云化学科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023084131-A2 | METHOD FOR PROCESSING A BIOMASS MATERIAL | PROIONIC GMBH (AT) | 2023-05-19 | — | — | WO | disclosed |
| CN-114477249-A | Method for preparing high-purity magnesium hydroxide and calcium sulfate by adopting calcium carbide furnace purification ash | 龙岩紫云化学科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-20200179254-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2020-06-11 | — | — | US | disclosed |
| US-20190240129-A1 | CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2019-08-08 | — | — | US | disclosed |
| US-20190216714-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2019-07-18 | — | — | US | disclosed |
| CN-104418825-A | Method for purifying lipstatin | UNIV PEKING FOUNDER GROUP CO | 2015-03-18 | — | — | CN | disclosed |
| CN-102333765-A | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst | TEIJIN PHARMA LTD | 2012-01-25 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5672497-A | ADDING DNA SEQUENCE | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0238323-B1 | Improvements in or relating to tylosin antibiotic-producing microorganisms | LILLY CO ELI (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0361905-A2 | Carbomycin biosynthetic genes, designated carL and carM, for use in streptomyces and other organisms | ELI LILLY AND COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0238323-A2 | Improvements in or relating to tylosin antibiotic-producing microorganisms | ELI LILLY AND COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0035820-B1 | NOVEL QUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHOD FOR THE PREPARATION OF THESE COMPOUNDS | ACF CHEMIEFARMA NV (NL) | 1984-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240129-A1 | CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, CUTA, S100A10 | HDAC3 778/4885HDAC1 121/4885HDAC2 372/4885 |
| US-20190216714-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, CD44, PCNA | HDAC3 803/4885HDAC1 116/4885HDAC2 207/4885 |
| US-20200179254-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, CUTA, DSG1 | HDAC3 406/4885HDAC1 62/4885HDAC2 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.