SCHEMBL5875745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5875742	0.82	ADORA3 (0.47)	ADORA3SLC6A3LOXL2LOXHTR6
	Thiazolsulfone SCHEMBL152559	0.82	ADORA3 (1.00)	ADORA3SLC6A3LOXL2LOXHTR6
	SCHEMBL5875692	0.80	ADORA3 (0.76)	ADORA3SLC6A3LOXL2LOXKCNH2
	SCHEMBL19392345	0.79	ALDH1A1 (0.45)	ADORA3SLC6A3LOXL2LOXALDH1A1
	SCHEMBL1062382	0.79	ADORA3 (0.75)	ADORA3SLC6A3LOXL2LOXHTR6
	SCHEMBL5875599	0.77	ADORA3 (0.58)	ADORA3SLC6A3LOXL2NAMPTALDH1A1
	SCHEMBL1062638	0.76	ADORA3 (0.69)	ADORA3SLC6A3ALDH1A1MEN1LMNA
	SCHEMBL27736703	0.72	HTR6 (0.55)	HTR6ALDH1A1MEN1LMNAMAPT
	4-Amino-4'-Hydroxamine-Diphenylsulphone SCHEMBL29349839	0.71	HTR6 (0.67)	HTR6ALDH1A1MEN1LMNAKMT2A
	SCHEMBL9048270	0.71	ADORA3 (0.62)	ADORA3SLC6A3LOXL2LOXKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.