Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5877634 | 0.89 | CASR (0.45) | GHSRPDE1APDE1BPDE1C | |
| SCHEMBL5877140 | 0.88 | ALDH1A1 (0.46) | PDE1APDE1BPDE1C | |
| SCHEMBL5877477 | 0.88 | ADORA3 (0.45) | GHSRPDE1APDE1BPDE1C | |
| SCHEMBL5877626 | 0.84 | ABCC1 (0.52) | GHSR | |
| SCHEMBL5878284 | 0.84 | EGFR (0.45) | PDE1APDE1BPDE1C | |
| SCHEMBL5877732 | 0.82 | ABCC1 (0.52) | GHSR | |
| SCHEMBL5877867 | 0.82 | GHSR (0.54) | GHSR | |
| SCHEMBL5877811 | 0.81 | ABCC1 (0.46) | GHSR | |
| SCHEMBL5876953 | 0.81 | ABCC1 (0.50) | GHSR | |
| SCHEMBL5877929 | 0.80 | CYP2D6 (0.42) | GHSRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060706-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-06-13 | — | — | US | disclosed |