Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878041 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HSD17B10NPC1KMT2AMAPT | |
| SCHEMBL5877277 | 0.88 | LMNA (0.46) | ALDH1A1HSD17B10NPC1KMT2AMAPT | |
| SCHEMBL5877273 | 0.88 | LMNA (0.46) | ALDH1A1HSD17B10NPC1KMT2AMAPT | |
| SCHEMBL5877219 | 0.82 | LMNA (0.39) | HSD17B10NPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5877223 | 0.82 | LMNA (0.39) | HSD17B10NPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7487746 | 0.79 | LMNA (0.37) | ALDH1A1KMT2AMAPTTHRBMEN1 | |
| SCHEMBL7487743 | 0.79 | LMNA (0.37) | ALDH1A1KMT2AMAPTTHRBMEN1 | |
| SCHEMBL5878481 | 0.78 | MAPT (0.40) | KMT2AMAPTMEN1LMNAADORA3 | |
| SCHEMBL5878477 | 0.78 | MAPT (0.40) | KMT2AMAPTMEN1LMNAADORA3 | |
| SCHEMBL5877477 | 0.78 | ADORA3 (0.45) | ALDH1A1ADORA3TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060706-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-06-13 | — | — | US | disclosed |