Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621286 | 0.80 | — | — | |
| SCHEMBL587834 | 0.80 | GABRA1 (0.34) | TSHR | |
| SCHEMBL3785333 | 0.76 | TSHR (0.50) | TSHR | |
| SCHEMBL10338763 | 0.75 | CYP1A2 (0.32) | — | |
| SCHEMBL4808650 | 0.74 | GABRA1 (0.48) | TSHR | |
| SCHEMBL30389926 | 0.74 | GABRA1 (0.48) | TSHR | |
| SCHEMBL588784 | 0.70 | GABRA1 (0.39) | TSHR | |
| SCHEMBL5422503 | 0.70 | GABRA1 (0.34) | TSHR | |
| SCHEMBL4143745 | 0.70 | P2RX7 (0.37) | TSHR | |
| SCHEMBL7306128 | 0.69 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1604964-B1 | ZERO-VALENCE TRANSITION METAL COMPLEX AND METHOD OF SYNTHESIZING ORGANOMETALLIC COMPOUND FROM THE SAME AS STARTING MATERIAL | SEKISUI CHEMICAL CO LTD (JP) | 2009-06-10 | — | — | EP | disclosed |
| EP-1431302-B1 | PROCESS FOR SYNTHESIS OF ORGANOMETALLIC COMPOUNDS | SEKISUI CHEMICAL CO LTD (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-7361776-B2 | Zero-valent transition metal complex and method for producing an organometallic compound using the same as a starting material | SEKISUI CHEMICAL CO., LTD. (JP) | 2008-04-22 | — | — | US | disclosed |
| US-7098355-B2 | Process for synthesis of organometallic compounds | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-08-29 | — | — | US | disclosed |
| US-20060149088-A1 | Zero-valence transition metal complex and method of synthesizing organometallic compound from the same as starting material | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-07-06 | — | — | US | disclosed |
| US-20060030723-A1 | Process for synthesis of organometallic compounds | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
| EP-1604964-A1 | ZERO-VALENCE TRANSITION METAL COMPLEX AND METHOD OF SYNTHESIZING ORGANOMETALLIC COMPOUND FROM THE SAME AS STARTING MATERIAL | SEKISUI CHEMICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1431302-A1 | PROCESS FOR SYNTHESIS OF ORGANOMETALLIC COMPOUNDS | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030723-A1 | Process for synthesis of organometallic compounds | CYP4F12, CYP4F2, CYP4F11 | TSHR 3234/4885 |
| US-20060149088-A1 | Zero-valence transition metal complex and method of synthesizing organometallic compound from the same as starting material | OSTC, PORCN, SQLE | TSHR 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.