Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879673 | 0.81 | HSD17B10 (0.63) | ALDH1A1HSD17B10MAPTLMNAKDM4E | |
| SCHEMBL5879789 | 0.81 | ITGB3 (0.44) | ALDH1A1HSD17B10KDM4EUSP2CASP1 | |
| SCHEMBL9886515 | 0.80 | KMT2A (0.60) | DTYMKALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL5879692 | 0.79 | NOS2 (0.48) | ALDH1A1HSD17B10MAPTKDM4EUSP2 | |
| SCHEMBL5879731 | 0.73 | HSD17B10 (0.64) | ALDH1A1HSD17B10MAPTLMNATSHR | |
| SCHEMBL5879838 | 0.72 | ITGB3 (0.49) | ALDH1A1HSD17B10 | |
| SCHEMBL4310756 | 0.72 | DTYMK (0.49) | DTYMKALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL5879645 | 0.69 | ITGB3 (0.61) | HSD17B10TSHRKDM4ECASP1CASP7 | |
| SCHEMBL29659287 | 0.68 | KMT2A (0.57) | DTYMKALDH1A1MAPTLMNACHRM2 | |
| SCHEMBL578012 | 0.68 | KMT2A (0.57) | DTYMKALDH1A1MAPTLMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |