Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879731 | 0.91 | HSD17B10 (0.64) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879692 | 0.86 | NOS2 (0.48) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879778 | 0.83 | ITGB3 (0.43) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879513 | 0.81 | DTYMK (0.46) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879601 | 0.80 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879789 | 0.79 | ITGB3 (0.44) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879590 | 0.73 | ITGB3 (0.54) | HSD17B10SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5879838 | 0.72 | ITGB3 (0.49) | HSD17B10ALDH1A1 | |
| SCHEMBL5879751 | 0.72 | ITGB3 (0.49) | L3MBTL1ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL5879664 | 0.71 | ITGB3 (0.52) | ALDH1A1KDM4EGAAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |