Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879673 | 0.86 | HSD17B10 (0.63) | HSD17B10ALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5879513 | 0.79 | DTYMK (0.46) | HSD17B10ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5879789 | 0.78 | ITGB3 (0.44) | HSD17B10ALDH1A1MEN1KMT2AITGB3 | |
| SCHEMBL5879731 | 0.78 | HSD17B10 (0.64) | HSD17B10ALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5879751 | 0.76 | ITGB3 (0.49) | ALDH1A1MEN1KMT2AITGB3ITGAV | |
| SCHEMBL5879664 | 0.75 | ITGB3 (0.52) | ALDH1A1MEN1KMT2AITGB3ITGAV | |
| SCHEMBL5879778 | 0.75 | ITGB3 (0.43) | HSD17B10ALDH1A1KMT2AITGB3ITGAV | |
| SCHEMBL5879838 | 0.75 | ITGB3 (0.49) | HSD17B10ALDH1A1ITGB3ITGAV | |
| Acetic Acid SCHEMBL5879702 | 0.74 | ITGB3 (0.61) | HSD17B10ALDH1A1ITGB3ITGAV | |
| SCHEMBL5879510 | 0.73 | GRIN2B (0.41) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |