Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264029 | 0.90 | NPSR1 (0.56) | TRPM8NPSR1KMT2AMEN1HPGD | |
| SCHEMBL5121109 | 0.84 | ALDH1A1 (0.48) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28100021 | 0.84 | ACHE (0.46) | TRPM8PTGIRHPGDRAB9AALDH1A1 | |
| SCHEMBL2091758 | 0.80 | TRPM8 (0.56) | TRPM8PTGIRNPSR1KMT2AMEN1 | |
| SCHEMBL2091757 | 0.79 | TRPM8 (0.54) | TRPM8PTGIRNPSR1KMT2AMEN1 | |
| SCHEMBL28100014 | 0.78 | HSD17B10 (0.56) | NPSR1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL12914594 | 0.78 | NPSR1 (0.61) | TRPM8NPSR1KMT2AMEN1HPGD | |
| SCHEMBL4811219 | 0.77 | TRPM8 (0.53) | TRPM8PTGIRNPSR1KMT2AMEN1 | |
| SCHEMBL5932651 | 0.77 | TRPM8 (0.53) | TRPM8PTGIRNPSR1KMT2AMEN1 | |
| SCHEMBL77003 | 0.77 | TRPM8 (0.53) | TRPM8PTGIRNPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153925-B2 | Condensation polymers from N, N*-disubstituted disulfonamides | PEWS R GARTH | 2006-12-26 | — | — | US | disclosed |
| US-20060128924-A1 | Novel condensation polymers from N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |