Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.42 |
| ▸ | ATP4B | P51164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884812 | 0.91 | LMNA (0.43) | ATP4AATP4BLMNAMAPTGAA | |
| SCHEMBL5884324 | 0.80 | PPARG (0.46) | ATP4AATP4BMAPTGAAKMT2A | |
| SCHEMBL5884475 | 0.77 | TDP1 (0.41) | LMNAMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9384155 | 0.77 | LMNA (0.50) | LMNAMAPTGAAKMT2ALTA4H | |
| SCHEMBL5884362 | 0.75 | NR1I2 (0.38) | MAPTGAAL3MBTL1 | |
| SCHEMBL5884624 | 0.74 | GPR119 (0.44) | GAAKCNH2 | |
| SCHEMBL5884332 | 0.74 | KMT2A (0.39) | GAAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5884268 | 0.73 | MEN1 (0.43) | LMNAKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5884262 | 0.73 | GPR119 (0.37) | GAAKMT2AALDH1A1KCNH2L3MBTL1 | |
| SCHEMBL5884261 | 0.73 | PPARG (0.37) | MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |