Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9379751 | 0.81 | KCNH2 (0.44) | ALDH1A1POLBMAPTHTT | |
| SCHEMBL5884812 | 0.79 | LMNA (0.43) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL5883853 | 0.77 | ATP4A (0.42) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL16648797 | 0.77 | MAPT (0.61) | LMNAALDH1A1POLBMAPTSMN1; SMN2 | |
| Pirodavir SCHEMBL146440 | 0.76 | HRH3 (0.46) | LMNAALDH1A1MAPTHTTKMT2A | |
| SCHEMBL9209752 | 0.76 | HRH3 (0.44) | LMNAALDH1A1MAPTHTT | |
| SCHEMBL9218008 | 0.76 | KDM4E (0.44) | ALDH1A1MAPTHTT | |
| SCHEMBL9380742 | 0.74 | HTR1A (0.60) | SMN1; SMN2TP53 | |
| SCHEMBL9381746 | 0.74 | KCNH2 (0.44) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9381992 | 0.74 | KCNH2 (0.50) | ALDH1A1POLBMAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398425-B1 | Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA NV (BE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0398425-A1 | Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-11-22 | — | — | EP | disclosed |