Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884608 | 0.91 | HPGD (0.40) | OPRK1PPARGPPARDGPR119OGA | |
| SCHEMBL5884665 | 0.91 | PPARG (0.38) | OPRK1PPARGPPARDGPR119OGA | |
| SCHEMBL5884899 | 0.89 | GPR119 (0.36) | OPRK1PPARGPPARDGPR119OGA | |
| SCHEMBL5884645 | 0.87 | OPRK1 (0.36) | OPRK1PPARGPPARDGPR119OGA | |
| SCHEMBL5884689 | 0.87 | KCNH2 (0.39) | OPRK1GPR119NR1I2HPGDMAPT | |
| SCHEMBL5884333 | 0.87 | KCNH2 (0.39) | OPRK1GPR119NR1I2HPGDMAPT | |
| SCHEMBL5884592 | 0.85 | NPC1 (0.35) | OPRK1PPARGPPARDGPR119PPARA | |
| SCHEMBL5884657 | 0.84 | OPRK1 (0.36) | OPRK1PPARGPPARDGPR119OGA | |
| SCHEMBL5884102 | 0.82 | MEN1 (0.46) | OPRK1PPARGPPARDGPR119PPARA | |
| SCHEMBL5884132 | 0.82 | LMNA (0.39) | OPRK1PPARGPPARDGPR119PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |