Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884132 | 0.91 | LMNA (0.39) | HPGDOPRK1ALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL5884543 | 0.91 | OPRK1 (0.38) | HPGDOPRK1MEN1KMT2APPARG | |
| SCHEMBL5884689 | 0.85 | KCNH2 (0.39) | HPGDOPRK1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL5884333 | 0.85 | KCNH2 (0.39) | HPGDOPRK1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL5884657 | 0.84 | OPRK1 (0.36) | HPGDOPRK1ALDH1A1PPARGPPARD | |
| SCHEMBL5884645 | 0.84 | OPRK1 (0.36) | OPRK1PPARGPPARDGPR119OGA | |
| SCHEMBL5884592 | 0.84 | NPC1 (0.35) | OPRK1PPARGPPARDGPR119NPC1 | |
| SCHEMBL5884665 | 0.83 | PPARG (0.38) | HPGDOPRK1PPARGPPARDGPR119 | |
| SCHEMBL5884899 | 0.83 | GPR119 (0.36) | OPRK1PPARGPPARDGPR119MAPT | |
| SCHEMBL5884102 | 0.81 | MEN1 (0.46) | OPRK1MEN1KMT2APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |