Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884899 | 0.90 | GPR119 (0.36) | GPR119NR1I2PPARGPPARDPPARA | |
| SCHEMBL5884665 | 0.88 | PPARG (0.38) | GPR119NR1I2PPARGPPARDPPARA | |
| SCHEMBL5884362 | 0.86 | NR1I2 (0.38) | GPR119NR1I2TEAD1TEAD3MAPT | |
| SCHEMBL5884326 | 0.84 | NPC1 (0.38) | GPR119PPARGPPARDPPARATEAD1 | |
| SCHEMBL5884479 | 0.82 | CTSS (0.35) | NR1I2PPARGPPARDPPARAOGA | |
| SCHEMBL5884356 | 0.81 | HRH3 (0.38) | GPR119NR1I2DRD2MAPT | |
| SCHEMBL5884729 | 0.80 | NPC1 (0.37) | SMN1; SMN2GLS | |
| SCHEMBL5884402 | 0.79 | OPRK1 (0.33) | NR1I2PPARGPPARDPPARAOGA | |
| SCHEMBL5884543 | 0.79 | OPRK1 (0.38) | GPR119NR1I2PPARGPPARDPPARA | |
| SCHEMBL5884805 | 0.78 | NR1I2 (0.32) | NR1I2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |