Methacrylic Acid

Methacrylic Acid

SCHEMBL5886130

C1=CC2CC1C1CCCC21.C=C(C)C(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
APEX1 P27695 1/20 0.39
HSD11B1 P28845 2/20 0.39
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD11B2 P80365 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL4202813 0.79 HSD11B1 (0.39) TDP1HSD11B1ALDH1A1
SCHEMBL5886167 0.79 THRB (0.40) POLBTDP1HSD11B1KMT2ASMN1; SMN2
Acrylic Acid SCHEMBL4301317 0.78 LMNA (0.40) POLBTDP1APEX1HSD11B1SMN1; SMN2
Ethylene SCHEMBL774849 0.76 ALDH1A1 (0.39) HSD11B1ALDH1A1
Methacrylic Acid SCHEMBL17181023 0.76 HSD11B1 (0.35) TDP1HSD11B1KMT2AALDH1A1
SCHEMBL3986309 0.76 ALDH1A1 (0.42) HSD11B1ALDH1A1
SCHEMBL199996 0.76 ALDH1A1 (0.42) HSD11B1ALDH1A1
Methacrylic Acid SCHEMBL5971154 0.75 ALDH1A1 (0.63) POLBTDP1APEX1KMT2AALDH1A1
Methacrylic Acid SCHEMBL422384 0.75 ALDH1A1 (0.63) POLBTDP1APEX1KMT2AALDH1A1
Methacrylic Acid SCHEMBL4515900 0.74 POLB (0.35) POLBTDP1APEX1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084211-B2 Weatherproofing, waterproofing; addition polymer-polyurethane copolymer KANSAI PAINT CO., LTD. (JP) 2006-08-01 US disclosed
US-20040072965-A1 Weatherproofing, waterproofing; addition polymer-polyurethane copolymer NAKAO TADAHIRO (JP) 2004-04-15 US disclosed
US-6509432-B2 Oxidative curable silicon modified vinyl-based resin obtained by combining an epoxy group-containing vinyl copolymer with an unsaturated fatty acid and a silicone resin with a hydroxyl and/or an alkoxyl group bonded to silicon KANSAI PAINT CO., LTD. (JP) 2003-01-21 US disclosed
US-20020010269-A1 Ordinary temperature curable coating composition KANSAI PAINT CO., LTD. (JP) 2002-01-24 US disclosed