Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588941 | 0.96 | CA1 (0.39) | BBOX1TSHRALDH1A1CYP3A4CA1 | |
| Lithium Ion SCHEMBL588849 | 0.96 | BBOX1 (0.37) | BBOX1TSHRALDH1A1CYP3A4CA1 | |
| Potassium Ion SCHEMBL28190006 | 0.88 | TSHR (0.34) | BBOX1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL588136 | 0.88 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28190609 | 0.84 | FFAR3 (0.34) | BBOX1TSHRALDH1A1CYP3A4CA1 | |
| SCHEMBL28495861 | 0.83 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2776924 | 0.81 | TSHR (0.48) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL588137 | 0.80 | TSHR (0.48) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL301337 | 0.79 | TSHR (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL588940 | 0.78 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114819-B2 | Polymers for oilfield applications | BAKER HUGHES INCORPORATED (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100105580-A1 | Polymers For Oilfield Applications | BJ SERVICES COMPANY (US) | 2010-04-29 | — | — | US | disclosed |