Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887162 | 1.00 | TACR1 (0.53) | TACR1TP53ITGB3ITGA2BACACB | |
| SCHEMBL25669503 | 0.88 | TACR1 (0.59) | TACR1TP53ITGB3ITGA2BACACB | |
| SCHEMBL5887308 | 0.88 | ATM (0.50) | TACR1LMNA | |
| SCHEMBL2520016 | 0.88 | ATM (0.50) | TACR1LMNA | |
| SCHEMBL12453492 | 0.88 | TACR1 (0.59) | TACR1TP53ITGB3ITGA2BACACB | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL14370511 | 0.87 | TACR1 (0.58) | TACR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468858 | 0.87 | TACR1 (0.58) | TACR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468756 | 0.87 | TACR1 (0.58) | TACR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL25257912 | 0.85 | TACR1 (0.56) | TACR1CTSSCTSK | |
| SCHEMBL5887222 | 0.85 | TACR1 (0.53) | TACR1TP53ITGB3ITGA2BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091373-B2 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | TACR1 2442/4885TP53 4249/4885ITGB3 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.