Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448364 | 0.94 | APOBEC3G (0.59) | APOBEC3GSLC6A4SLC6A2TDP1SLC6A3 | |
| SCHEMBL9763265 | 0.82 | CHRM2 (0.46) | APOBEC3GSLC6A4SLC6A2TDP1SLC6A3 | |
| SCHEMBL27752842 | 0.80 | APOBEC3G (0.43) | APOBEC3GSLC6A4SLC6A2TDP1ALDH1A1 | |
| SCHEMBL4442278 | 0.80 | APOBEC3G (0.73) | APOBEC3GSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL29534868 | 0.79 | TDP1 (0.55) | APOBEC3GTDP1ALDH1A1 | |
| SCHEMBL31203 | 0.79 | TDP1 (0.55) | APOBEC3GTDP1ALDH1A1 | |
| SCHEMBL6535453 | 0.77 | TAAR1 (0.54) | SLC6A4P4HB | |
| SCHEMBL3887461 | 0.77 | POLB (0.55) | APOBEC3GTDP1LMNAALDH1A1 | |
| SCHEMBL5147860 | 0.77 | APOBEC3G (0.55) | APOBEC3GSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4143747 | 0.76 | LMNA (0.44) | APOBEC3GSLC6A4SLC6A2TDP1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | claimed |
| CN-111393683-B | Modified cationic microgel and preparation method and application thereof | 广东科德环保科技股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-8115046-B2 | Micro encapsulation composition for hydrocarbons and detoxification of highly hazardous chemicals and substances | RTA SYSTEMS, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-7825253-B2 | 2-aminoquinoline derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-11-02 | — | — | US | disclosed |
| CN-101622227-A | Biaryl and biheteroaryl compounds useful in treating iron disorders | XENON PHARMACEUTICALS INC | 2010-01-06 | — | — | CN | disclosed |
| US-20090245939-A1 | DUAL-USE MICRO ENCAPSULATION COMPOSITION FOR HYDROCARBONS AND DETOXIFICATION OF HIGHLY HAZARDOUS CHEMICALS AND SUBSTANCES | RTA SYSTEMS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| EP-2061754-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008115999-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |
| US-20080234384-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | US | disclosed |
| US-7288549-B2 | Heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents | AVENTIS PHARMA S.A. (FR) | 2007-10-30 | — | — | US | disclosed |
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |
| US-20050245505-A1 | Novel heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents | ENTASIS THERAPEUTICS LIMITED (GB) | 2005-11-03 | — | — | US | disclosed |
| EP-1399444-A2 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100860-A2 | HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-12-19 | — | — | WO | disclosed |
| US-5177211-A | Anti-platelet aggregation and anti-hypotensive | ALTER, S.A. (ES) | 1993-01-05 | — | — | US | disclosed |
| EP-0325187-B1 | 4-ALKYL-1, 4-DIHYDROPYRIDINES WITH PAF-ANTAGONIST ACTIVITY | ALTER, S.A. (ES) | 1992-11-11 | — | — | EP | disclosed |
| EP-0325187-A1 | 4-alkyl-1, 4-dihydropyridines with PAF-antagonist activity | ALTER, S.A. (ES) | 1989-07-26 | — | — | EP | disclosed |
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234384-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | FECH, SLC10A1, SLC40A1 | APOBEC3G 2840/4885SLC6A4 724/4885SLC6A2 247/4885 |
| US-20050245505-A1 | Novel heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents | FDPS, MRPL21, DHPS | APOBEC3G 3776/4885SLC6A4 4171/4885SLC6A2 2495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.