Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374279 | 0.74 | TDP1 (0.39) | RAPGEF4RETKIF5BMAPTGAA | |
| SCHEMBL7938078 | 0.73 | TRPA1 (0.54) | RAPGEF4RETKIF5BMAPTGAA | |
| SCHEMBL28044335 | 0.73 | MAPT (0.50) | RETKIF5BMAPTGAAALDH1A1 | |
| SCHEMBL11451246 | 0.68 | RET (0.41) | RAPGEF4RETKIF5BMAPTGAA | |
| SCHEMBL3228186 | 0.65 | MAPT (0.52) | MAPTGAAALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL27722164 | 0.64 | TRPA1 (0.48) | RETKIF5BMAPTGAAALDH1A1 | |
| SCHEMBL1321007 | 0.64 | RET (0.52) | RETKIF5BMAPTGAALMNA | |
| SCHEMBL22169138 | 0.64 | CXCR2 (0.50) | IDO1TDO2MAPTGAAALDH1A1 | |
| SCHEMBL8310698 | 0.64 | TRPA1 (0.52) | RETKIF5BIDO1MAPTGAA | |
| SCHEMBL11406396 | 0.64 | TRPA1 (0.52) | RETKIF5BMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7077872-B2 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AG (DE) | 2006-07-18 | — | — | US | claimed |