Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIF5B | P33176 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374279 | 0.85 | TDP1 (0.39) | RETKIF5BTRPA1ATMRAPGEF4 | |
| SCHEMBL7938078 | 0.84 | TRPA1 (0.54) | RETKIF5BTRPA1ATMRAPGEF4 | |
| SCHEMBL5685310 | 0.78 | L3MBTL1 (0.42) | RETKIF5BTRPA1ATMGAA | |
| SCHEMBL28044335 | 0.73 | MAPT (0.50) | RETKIF5BTRPA1ATMGAA | |
| SCHEMBL3228186 | 0.72 | MAPT (0.52) | TRPA1ATMGAAKMT2AKDM4E | |
| SCHEMBL22661276 | 0.71 | CDC25B (0.51) | GAAKMT2AKDM4EMAPTTDP1 | |
| SCHEMBL11569807 | 0.70 | ALDH1A1 (0.41) | TRPA1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL1321007 | 0.70 | RET (0.52) | RETKIF5BTRPA1ATMGAA | |
| SCHEMBL27561408 | 0.70 | RET (0.40) | RETKIF5BTRPA1ATMRAPGEF4 | |
| SCHEMBL8310698 | 0.70 | TRPA1 (0.52) | RETKIF5BTRPA1ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011843-A2 | Developing components for hair oxydation dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |