Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KIF5B | P33176 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451246 | 0.85 | RET (0.41) | TDP1CYP3A4RECQLRETKIF5B | |
| SCHEMBL28044335 | 0.83 | MAPT (0.50) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL1417442 | 0.83 | CXCR2 (0.42) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL17498278 | 0.80 | CA14 (0.44) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL7938078 | 0.80 | TRPA1 (0.54) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL17498320 | 0.80 | ALOX15 (0.41) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL17538442 | 0.77 | ALOX15 (0.45) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL17498295 | 0.75 | ALDH1A1 (0.50) | TDP1CYP3A4RECQLHIF1AALDH1A1 | |
| SCHEMBL5685310 | 0.74 | L3MBTL1 (0.42) | TDP1RETKIF5BTRPA1ATM | |
| SCHEMBL5889185 | 0.74 | RAPGEF4 (0.41) | TDP1CYP3A4HIF1AALDH1A1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854449-A1 | Dying and/or lightening agent with cyanates | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-14 | — | — | EP | disclosed |