Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891267 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL18424825 | 0.96 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL5890635 | 0.89 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL18424824 | 0.88 | PTGS2 (0.64) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL48861 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10TDP1PTGS2CA12 | |
| SCHEMBL21993320 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10TDP1PTGS2CA12 | |
| SCHEMBL28971555 | 0.81 | ALOX5 (0.52) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL29543451 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL27691428 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 | |
| SCHEMBL5174552 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053173-B2 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-05-30 | — | — | US | claimed |
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-05-13 | — | — | US | claimed |
| EP-1380572-A1 | POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2004-01-14 | — | — | EP | claimed |
| US-7053173-B2 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1380572-A1 | POLYMERCAPTOPOLYPHENYLS AND METHOD FOR SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092775-A1 | Polymercaptopolyphenyl and process for preparation thereof | TMT1A, MSMO1, TST | ALDH1A1 1396/4885HSD17B10 2246/4885TDP1 1749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.