Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | DRD1 | P21728 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 7/20 | 0.42 |
| ▸ | DRD5 | P21918 | 7/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824901 | 0.82 | PRMT3 (0.36) | — | |
| SCHEMBL3168555 | 0.76 | QDPR (0.32) | — | |
| SCHEMBL3173976 | 0.75 | ABCB1 (0.42) | HTR1ADRD1DRD4DRD5DRD3 | |
| SCHEMBL11390969 | 0.75 | HTR1A (0.37) | HTR1ADRD1DRD4DRD5DRD3 | |
| SCHEMBL4630963 | 0.75 | ADRA1D (0.32) | DRD3DRD2 | |
| SCHEMBL27992066 | 0.72 | TLR9 (0.30) | — | |
| SCHEMBL9637964 | 0.70 | HTR1A (0.34) | HTR1ADRD1DRD4DRD5DRD3 | |
| SCHEMBL6578631 | 0.70 | DRD1 (0.33) | HTR1ADRD1DRD4DRD5DRD3 | |
| SCHEMBL8872933 | 0.69 | — | — | |
| SCHEMBL28109507 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874105-B | Preparation method of visible light and water promoted homoallylic amine compound | 大连理工大学 | 2023-03-03 | — | — | CN | claimed |
| CN-114874105-A | Preparation method of visible light and water promoted homoallylic amine compound | 大连理工大学 | 2022-08-09 | — | — | CN | claimed |
| EP-0245960-B1 | PROCESS FOR PREPARING N-ACYLTETRAHYDROISOQUINOLINE | Takasago Perfumery Co., Ltd. (JP) | 1992-07-29 | — | — | EP | claimed |
| CN-110891938-B | Tetrahydro-benzo [ D ] azepine derivatives as GPR120 modulators | 卡尔丹治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-115772169-A | Indoline [2,1-a ] isoquinoline derivative, preparation method and application | 郑州大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-114874105-B | Preparation method of visible light and water promoted homoallylic amine compound | 大连理工大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-110891938-A | Tetrahydro-benzo [ D ] azepin slow derivatives as GPR120 modulators | 卡尔丹治疗有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-104324754-A | Preparation method and application of bimetallic catalytic photo-functional POM/MOFs | UNIV DALIAN TECH | 2015-02-04 | — | — | CN | disclosed |
| EP-1751111-B1 | SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2014-12-31 | — | — | EP | disclosed |
| US-8188082-B2 | 5,6,7,8-tetrahydro-imidazo[1,5-α]pyrazine derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-05-29 | — | — | US | disclosed |
| EP-2125823-B1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |
| EP-0514851-A1 | N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme a:cholesterol acyl transferase | SCHERING CORPORATION (US) | 1992-11-25 | — | — | EP | disclosed |
| EP-0245960-B1 | PROCESS FOR PREPARING N-ACYLTETRAHYDROISOQUINOLINE | Takasago Perfumery Co., Ltd. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5124337-A | Treating atherosclerosis | SCHERING CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| US-5124337-A | Treating atherosclerosis | SCHERING CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0245960-A2 | Process for preparing N-acyltetrahydroisoquinoline | Takasago Perfumery Co., Ltd. (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0245960-A2 | Process for preparing N-acyltetrahydroisoquinoline | Takasago Perfumery Co., Ltd. (JP) | 1987-11-19 | — | — | EP | disclosed |