SCHEMBL808104

SCHEMBL808104

Cc1ccc(S(=O)(=O)Nc2ccc(O)c3ccccc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 1.00
KAT2B Q92831 2/20 1.00
KAT8 Q9H7Z6 2/20 1.00
KEAP1 Q14145 3/20 0.82
NFE2L2 Q16236 3/20 0.82
HKDC1 Q2TB90 3/20 0.74
MEN1 O00255 5/20 0.72
KMT2A Q03164 5/20 0.72
GAA P10253 4/20 0.72
ALDH1A1 P00352 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
GFER P55789 2/20 0.72
LMNA P02545 2/20 0.72
MAPT P10636 2/20 0.72
L3MBTL1 Q9Y468 2/20 0.72
PSD A5PKW4 1/20 0.72
MITF O75030 1/20 0.72
TP53 P04637 1/20 0.72
THRB P10828 1/20 0.72
HPGD P15428 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5307424 0.91 EP300 (0.83) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL589708 0.87 HKDC1 (0.77) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL28735044 0.85 EP300 (0.73) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL17298738 0.84 PSD (1.00) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL21511039 0.84 GAA (1.00) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL13765236 0.84 KEAP1 (0.86) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL14478903 0.83 EP300 (0.71) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL26241643 0.81 TDP1 (0.97) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL2068293 0.81 HKDC1 (0.70) EP300KAT2BKAT8KEAP1NFE2L2
SCHEMBL1348234 0.81 LMNA (0.75) EP300KAT2BKAT8KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3056198-A2 USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES MSP Co., Ltd (KR) 2016-08-17 EP claimed
EP-2617415-B1 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) 2016-04-20 EP claimed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US claimed
US-9068166-B2 Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2015-06-30 US claimed
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-09-12 US claimed
EP-2617415-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS Industry-Academic Cooperation Foundation, Yonsei University (KR) 2013-07-24 EP claimed
US-9834022-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2017-12-05 US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
US-20160332469-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2016-11-17 US disclosed
EP-3056198-A2 USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES MSP Co., Ltd (KR) 2016-08-17 EP disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
EP-2617415-B1 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) 2016-04-20 EP disclosed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US disclosed
EP-2617415-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS Industry-Academic Cooperation Foundation, Yonsei University (KR) 2013-07-24 EP disclosed
US-8288313-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-16 US disclosed
WO-2012036512-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS 연세대학교 산학협력단 (KR) 2012-03-22 WO disclosed
US-20100069240-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2010-03-18 US disclosed
US-20070026259-A1 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2007-02-01 US disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
US-4108663-A MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes COL2A1, MYADM, COL1A1 EP300 1142/4885KAT2B 2047/4885KAT8 3219/4885
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells COL2A1, MYADM, COL1A1 EP300 1167/4885KAT2B 2130/4885KAT8 3026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.