Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436852 | 0.81 | PIN1 (0.59) | HSD17B10KMT2AKDM4ETUBB4ATUBB | |
| SCHEMBL544668 | 0.78 | SMAD3 (0.41) | ERAP1AMY1A | |
| SCHEMBL855805 | 0.76 | MCHR1 (0.33) | TDP1 | |
| SCHEMBL251109 | 0.75 | LMNA (0.53) | HSD17B10MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL11839896 | 0.74 | MEN1 (0.37) | MAPTMEN1KMT2AMCL1NPC1 | |
| SCHEMBL11096785 | 0.74 | TDP1 (0.35) | MAPTKMT2AKDM4EMMP2TDP1 | |
| SCHEMBL830501 | 0.73 | KDM4E (0.34) | HSD17B10MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3388847 | 0.73 | ALDH1A1 (0.65) | FABP6MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL4279399 | 0.73 | HPGD (0.51) | FABP6MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11217318 | 0.73 | PIN1 (0.65) | HSD17B10FABP6ATMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125883-B1 | Integrin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2006-10-24 | — | — | US | disclosed |