Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | MC1R | Q01726 | 3/20 | 0.58 |
| ▸ | MC5R | P33032 | 2/20 | 0.58 |
| ▸ | MC3R | P41968 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119267 | 0.87 | HRH3 (0.59) | HRH3MC1RMC5RMC3RKMT2A | |
| SCHEMBL1514620 | 0.85 | HRH3 (0.54) | HRH3KMT2AMEN1MAPTGPR84 | |
| SCHEMBL11178183 | 0.83 | KMT2A (0.64) | HRH3KMT2AMEN1MAPTGPR84 | |
| SCHEMBL6599683 | 0.83 | HTR2A (0.71) | HRH3MC1RMC5RMC3RKMT2A | |
| SCHEMBL12845369 | 0.82 | HRH3 (0.54) | HRH3MC1RMC5RMC3RKMT2A | |
| Hydrochloric Acid SCHEMBL11602872 | 0.81 | HTR2A (0.70) | HRH3MC1RMC5RMC3RKMT2A | |
| SCHEMBL30275174 | 0.81 | GPR84 (0.59) | HRH3GPR84LMNAHTR2AHTR1A | |
| SCHEMBL11178205 | 0.81 | GPR84 (0.59) | HRH3GPR84HTR2AHTR1AHTR7 | |
| SCHEMBL8263301 | 0.81 | PTGS2 (0.53) | HRH3MC1RMC5RMC3RKMT2A | |
| SCHEMBL11169278 | 0.80 | MAPT (0.58) | HRH3MC1RMC5RMC3RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | claimed |
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| US-7060830-B2 | Synthesized γ-carbolines | GEORGE MASON INTELLECTUAL PROPERTIES, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| US-20050131010-A1 | Synthesized gamma-carbolines | WYNNE JAMES H (US) | 2005-06-16 | — | — | US | disclosed |
| US-4372887-A | DIURETIC, ANTITHROMBOGENIC, SMOOTH MUSCLE RELAXANTS | MEAD JOHNSON & COMPANY (US) | 1983-02-08 | — | — | US | disclosed |
| US-4259238-A | ANTIARRHYTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
| US-4196212-A | DIURETIC, ANTITHROMBOGENIC, SMOOTH MUSCLE RELAXANT, ANTIINFLAMMATORY | MEAD JOHNSON & COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4072675-A | DIURETICS, ANTICOAGULANTS, INOTROPIC AGENTS, ANTIINFLAMMATORY AGENTS, ANTIARRHYTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
| US-4049714-A | DIURETIC, ANTITHROMBOGENIC, ANTIARRYTHMIC, ANTIINFLAMMATORY, MUSCLE RELAXANTS | MEAD JOHNSON & COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131010-A1 | Synthesized gamma-carbolines | SNCA, PARK7, PRNP | HRH3 469/4885MC1R 1933/4885MC5R 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.