Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001103 | 0.86 | SCN5A (0.48) | CES2ALDH1A1GAAMAPTSCN5A | |
| SCHEMBL5898532 | 0.85 | CES2 (0.44) | CES2ALDH1A1LMNASCN5ASCN9A | |
| SCHEMBL6260645 | 0.75 | ALDH1A1 (0.41) | CES2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL3837958 | 0.75 | MAPT (0.55) | LMNAMAPTSCN5ASCN9A | |
| SCHEMBL13946506 | 0.75 | MAPT (0.55) | LMNAMAPTSCN5ASCN9A | |
| SCHEMBL13946510 | 0.75 | MAPT (0.55) | LMNAMAPTSCN5ASCN9A | |
| SCHEMBL8356496 | 0.74 | KCNN4 (0.55) | MAPTSCN5ASCN9A | |
| SCHEMBL4005874 | 0.73 | CES2 (0.42) | CES2ALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL4031527 | 0.71 | MAPT (0.50) | CES2GAAMAPTRPS6KA3JAK3 | |
| SCHEMBL8360666 | 0.70 | SCN5A (0.49) | ALDH1A1LMNAMAPTSCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
| WO-2003091201-A1 | DL-HYDROXY-ALKYL-PHENYLAMIDES HAVING ANTICONVULSIVE ACTIVITY | MEZA TOLEDO SERGIO ENRIQUE (MX) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | GABRB2, HRH3, HRH4 | CES2 146/4885ALDH1A1 905/4885LMNA 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.