SCHEMBL589904

SCHEMBL589904

C=Cc1c(Cl)cc(C)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
RAPGEF4 Q8WZA2 8/20 0.34
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11852191 0.84 GABRA1 (0.44) TP53TDP1HPGDALDH1A1LMNA
SCHEMBL15569271 0.80 GABRA1 (0.33) HPGDALDH1A1
SCHEMBL320209 0.78 ALDH1A1 (0.45) TP53TDP1RAPGEF4HPGDTSHR
SCHEMBL6388607 0.76 ALDH1A1 (0.38) TP53TDP1RAPGEF4ALDH1A1KMT2A
SCHEMBL6388612 0.76 TDP1 (0.36) TP53TDP1TSHRALDH1A1LMNA
SCHEMBL5605195 0.74 RAPGEF4 (0.34) RAPGEF4ALDH1A1LMNAKMT2A
SCHEMBL6111862 0.74 ALDH1A1 (0.50) TDP1RAPGEF4TSHRALDH1A1LMNA
SCHEMBL9126808 0.73 CYP3A4 (0.36) RAPGEF4
SCHEMBL22579527 0.73 ALDH1A1 (0.38) TP53TDP1HPGDALDH1A1LMNA
SCHEMBL183056 0.73 RAPGEF4 (0.44) RAPGEF4HPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050256217-A1 Monoalkenyl aromatic polyblend CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-11-17 US claimed
US-6492467-B1 PREPARATION OF A BLEND OF ABS POLYMERS IS DISCLOSED. THE INVENTION COMPRISES INTRODUCING A CORE/SHELL GRAFTED RUBBER IN THE FORM OF POWDER (CRUMB) TO AT LEAST ONE STAGE OF THE CONTINUOUS MASS POLYMERIZATION PROCESS FOR MAKING AN ABS BAYER CORPORATION 2002-12-10 US claimed
WO-2002090405-A2 A PROCESS FOR MAKING ABS POLYMERIC BLENDS BAYER POLYMERS LLC (US) 2002-11-14 WO claimed
US-5001192-A Polymeric polyblend composition THE DOW CHEMICAL COMPANY (US) 1991-03-19 US claimed
WO-2022209415-A1 MATTING POLYCARBONATE RESIN COMPOSITION 住化ポリカーボネート株式会社 2022-10-06 WO disclosed
EP-3044265-B1 MINERAL REINFORCED THERMOPLASTIC POLYMER COMPOSITIONS WITH IMPROVED PROPERTIES SABIC GLOBAL TECHNOLOGIES BV (NL) 2021-05-19 EP disclosed
EP-3055356-A1 FLAME RETARDANT THERMOPLASTIC COMPOSITIONS WITH IMPROVED PROPERTIES SABIC Global Technologies B.V. (NL) 2016-08-17 EP disclosed
EP-3044265-A2 MINERAL REINFORCED THERMOPLASTIC POLYMER COMPOSITIONS WITH IMPROVED PROPERTIES SABIC Global Technologies B.V. (NL) 2016-07-20 EP disclosed
EP-1587681-B1 A FORMABLE THERMOPLASTIC LAMINATE, A FORMED LAMINATE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-06-08 EP disclosed
US-9193860-B2 Thermoplastic molding composition based on AES rubber with low surface gloss BAYER MATERIALSCIENCE LLC (US) 2015-11-24 US disclosed
WO-2015069380-A2 MINERAL REINFORCED THERMOPLASTIC POLYMER COMPOSITIONS WITH IMPROVED PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-05-14 WO disclosed
WO-2015054179-A1 FLAME RETARDANT THERMOPLASTIC COMPOSITIONS WITH IMPROVED PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-04-16 WO disclosed
US-4083896-A Transparent polyblends MONSANTO COMPANY (US) 1978-04-11 US disclosed
US-4064093-A Process for preparing grafted rubber latices free of coagulum MONSANTO COMPANY (US) 1977-12-20 US disclosed
US-4042551-A Polymeric polyblends having improved melt flow MONSANTO COMPANY (US) 1977-08-16 US disclosed
US-3991136-A Method of producing ABS polyblends having a low residual monomer content MONSANTO COMPANY (US) 1976-11-09 US disclosed
US-3987124-A MASS AND SUSPENSION GRAFT POLYMERIZATION; PEROXIDE, FATTY ACID, AND HYDRATED SALT CATALYST SYSTEM MONSANTO COMPANY (US) 1976-10-19 US disclosed
US-3985693-A Polyvinyl chloride polyblend molding composition MONSANTO COMPANY (US) 1976-10-12 US disclosed
US-3959895-A Polyvinyl chloride polyblend molding MONSANTO COMPANY (US) 1976-06-01 US disclosed
US-3939225-A ADDITION COPOLYMER MONSANTO COMPANY (US) 1976-02-17 US disclosed