SCHEMBL183056

SCHEMBL183056

C=Cc1c(C)cc(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.44
ALDH1A1 P00352 3/20 0.36
AHR P35869 2/20 0.35
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP3A4 P08684 1/20 0.33
RECQL P46063 1/20 0.33
ABCB1 P08183 1/20 0.31
HTT P42858 1/20 0.31
HPGD P15428 1/20 0.30
CD44 P16070 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421109 1.00 RAPGEF4 (0.44) RAPGEF4ALDH1A1AHRTSHRHSD17B10
SCHEMBL28118820 0.88 TSHR (0.35) RAPGEF4AHRTSHRCYP3A4
SCHEMBL320209 0.83 ALDH1A1 (0.45) RAPGEF4ALDH1A1AHRTSHRHSD17B10
SCHEMBL19431565 0.75 RAPGEF4 (0.32) RAPGEF4
SCHEMBL15322142 0.74 AR (0.37) ALDH1A1
SCHEMBL589904 0.73 TP53 (0.34) RAPGEF4ALDH1A1TSHRHPGD
SCHEMBL9126808 0.73 CYP3A4 (0.36) RAPGEF4CYP3A4CD44
SCHEMBL8003615 0.72 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL18243708 0.69 ALDH1A1 (0.41) RAPGEF4ALDH1A1AHRTSHRHSD17B10
SCHEMBL5729812 0.69 ERN1 (0.41) RAPGEF4ALDH1A1TSHRHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260056485-A1 TONER AND IMAGE FORMING METHOD ZEON CORPORATION (JP) 2026-02-26 US disclosed
US-20260028459-A1 SURFACTANT COMPOSITION, COMPOSITION FOR EMULSION POLYMERIZATION, METHOD OF PRODUCING POLYMER EMULSION, AND POLYMER EMULSION ADEKA CORPORATION (JP) 2026-01-29 US disclosed
EP-4685199-A1 SURFACTANT COMPOSITION, COMPOSITION FOR EMULSION POLYMERIZATION, METHOD OF PRODUCING POLYMER EMULSION, AND POLYMER EMULSION ADEKA CORPORATION (JP) 2026-01-28 EP disclosed
US-20260008918-A1 CROSSLINKABLE POLYMER COMPOSITION, CROSSLINKED PRODUCT, AND CROSSLINKED FOAM ZEON CORPORATION (JP) 2026-01-08 US disclosed
EP-4675362-A1 TONER SET Zeon Corporation (JP) 2026-01-07 EP disclosed
EP-4675361-A1 TONER SET AND MAGENTA TONER Zeon Corporation (JP) 2026-01-07 EP disclosed
US-12460100-B2 Polymer latex for the preparation of an elastomeric film having excellent stress retention properties and softness SYNTHOMER SDN. BHD. (MY) 2025-11-04 US disclosed
US-20250333629-A1 ADHESIVE AGENT COMPOSITION, HOT-MELT ADHESIVE AGENT COMPOSITION, AND ADHESIVE AGENT ZEON CORPORATION (JP) 2025-10-30 US disclosed
EP-3357968-B1 BLOCK COPOLYMER COMPOSITION AND HOT MELT ADHESIVE COMPOSITION ZEON CORP (JP) 2025-10-15 EP disclosed
US-12378344-B2 Polymer latex composition for the preparation of an elastomeric film having self-healing properties SYNTHOMER SDN. BHD. (MY) 2025-08-05 US disclosed
EP-1634899-A1 Conjugated diene rubber gel, rubber compositions containing the same and process for production of conjugated diene rubber Zeon Corporation (JP) 2006-03-15 EP disclosed
US-20050124760-A1 Conjugated diene rubber gel, rubber compositions containing the same and process for production of conjugated diene rubber ZEON CORPORATION 2005-06-09 US disclosed
US-6897279-B2 Conjugated diene rubber gel, rubber compositions containing the same and process for production of conjugated diene rubber ZEON CORPORATION (JP) 2005-05-24 US disclosed
US-20040077814-A1 Conjugated diene rubber gel, rubber compositions containing the same and process for production of conjugated diene rubber ZEON CORPORATION 2004-04-22 US disclosed
US-6649724-B2 Synthetic latex rubbers suchg as butadiene-styrene copolymers, having wear and heat resistance, used for tires, coverings, belts, footwear, seals and as insulation ZEON CORPORATION (JP) 2003-11-18 US disclosed
US-6642315-B2 For use for a tire tread having a superior wet grip and abrasion resistance THE YOKOHAMA RUBBER CO., LTD. (JP) 2003-11-04 US disclosed
US-20030139523-A1 Conjugated diene rubber gel, rubber compositions containing the same and process for production of conjugated diene rubber ZEON CORPORATION (JP) 2003-07-24 US disclosed
US-20030055169-A1 Rubber composition and crosslinked rubber YOKOHAMA RUBBER CO., LTD., THE (JP) 2003-03-20 US disclosed
EP-1291369-A1 CONJUGATED DIENE RUBBER GEL, RUBBER COMPOSITIONS CONTAINING THE SAME AND PROCESS FOR PRODUCTION OF CONJUGATED DIENE RUBBER Zeon Corporation (JP) 2003-03-12 EP disclosed
EP-1245630-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER THE YOKOHAMA RUBBER CO., LTD. (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260056485-A1 TONER AND IMAGE FORMING METHOD ACTR5, COG1, COG4 RAPGEF4 1279/4885ALDH1A1 4545/4885AHR 4155/4885
US-20260008918-A1 CROSSLINKABLE POLYMER COMPOSITION, CROSSLINKED PRODUCT, AND CROSSLINKED FOAM RAD51, RAD1, FGB RAPGEF4 4143/4885ALDH1A1 772/4885AHR 404/4885
US-20260028459-A1 SURFACTANT COMPOSITION, COMPOSITION FOR EMULSION POLYMERIZATION, METHOD OF PRODUCING POLYMER EMULSION, AND POLYMER EMULSION SGMS1, PHOSPHO1, SGMS2 RAPGEF4 3487/4885ALDH1A1 3541/4885AHR 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.