Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | S100A9 | P06702 | 5/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899426 | 0.88 | ALDH1A1 (0.46) | MCL1HPGDMEN1CYP3A4CYP2D6 | |
| SCHEMBL5899466 | 0.86 | CA1 (0.50) | STSMAPTHPGDGAAKMT2A | |
| SCHEMBL14675961 | 0.75 | CA1 (0.55) | STSHPGDKMT2A | |
| SCHEMBL5899559 | 0.75 | ACLY (0.51) | ACLYBCL2L1MCL1LMNATP53 | |
| SCHEMBL14675973 | 0.75 | ALDH1A1 (0.46) | HPGDMEN1CYP3A4GAAKMT2A | |
| SCHEMBL5899422 | 0.72 | FLT1 (0.57) | LMNAMAPTMEN1GAAKMT2A | |
| SCHEMBL5963267 | 0.72 | CA1 (0.55) | STSHPGDMEN1KMT2A | |
| SCHEMBL14677077 | 0.71 | S100A9 (0.44) | LMNAMAPTS100A9HPGDCYP3A4 | |
| SCHEMBL4994999 | 0.70 | ALDH1A1 (0.50) | HPGDMEN1CYP1A2CYP3A4GAA | |
| SCHEMBL14676871 | 0.70 | ALDH1A1 (0.54) | LMNAMAPTHPGDCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | ACLY 1905/4885STS 66/4885BCL2L1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.