Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 10/20 | 0.61 |
| ▸ | MMP2 | P08253 | 9/20 | 0.61 |
| ▸ | MMP3 | P08254 | 8/20 | 0.61 |
| ▸ | MMP13 | P45452 | 8/20 | 0.61 |
| ▸ | MMP1 | P03956 | 7/20 | 0.61 |
| ▸ | MMP7 | P09237 | 7/20 | 0.61 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808878 | 0.91 | MMP2 (0.76) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL28849870 | 0.86 | MMP2 (0.56) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL7401982 | 0.86 | SLC1A2 (0.60) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL13335276 | 0.85 | SMN1; SMN2 (0.50) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL14419201 | 0.85 | MMP9 (0.56) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL6561375 | 0.85 | MMP2 (0.82) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL3973093 | 0.85 | MMP2 (0.82) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL21451101 | 0.85 | MMP2 (0.82) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL690201 | 0.84 | MMP2 (0.68) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL6723663 | 0.84 | MMP9 (0.72) | MMP9MMP2MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | MMP9 232/4885MMP2 1212/4885MMP3 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.