Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 11/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 10/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 10/20 | 0.60 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899567 | 0.86 | MMP9 (0.61) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| SCHEMBL13335276 | 0.81 | SMN1; SMN2 (0.50) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| SCHEMBL11578980 | 0.79 | ADAMTS4 (0.59) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| SCHEMBL8648587 | 0.79 | SLC1A2 (0.76) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| SCHEMBL12808878 | 0.78 | MMP2 (0.76) | MMP9MMP2MMP3MMP13ADAMTS4 | |
| SCHEMBL7397814 | 0.77 | POLB (0.50) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| SCHEMBL7315790 | 0.77 | POLB (0.50) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL7315781 | 0.76 | POLB (0.49) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL7315786 | 0.76 | POLB (0.49) | SLC1A2SLC1A3SLC1A1MMP9MMP2 | |
| SCHEMBL11588570 | 0.76 | SLC1A2 (1.00) | SLC1A2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714295-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-0714295-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714295-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5397791-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1995004531-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-16 | — | — | WO | disclosed |