Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236205 | 0.90 | HPGD (0.56) | ALDH1A1POLBL3MBTL1CTDSP1MEN1 | |
| Hydrochloric Acid SCHEMBL27610313 | 0.89 | HPGD (0.54) | ALDH1A1POLBL3MBTL1CTDSP1MEN1 | |
| Acetone SCHEMBL29448975 | 0.87 | HPGD (0.53) | ALDH1A1POLBL3MBTL1CTDSP1MEN1 | |
| SCHEMBL27504010 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL9495815 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRPOLBL3MBTL1CTDSP1 | |
| SCHEMBL9498848 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL9495408 | 0.78 | NPC1 (0.58) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL27905517 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1POLBL3MBTL1CTDSP1MEN1 | |
| SCHEMBL358221 | 0.77 | POLB (0.60) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL11792109 | 0.76 | SMN1; SMN2 (0.61) | ALDH1A1TSHRPOLBL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135785-A1 | Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof | PIERRE FABRE MEDICAMENT (FR) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135785-A1 | Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof | ACAT2, ACAT1, LCAT | ALDH1A1 195/4885TSHR 4783/4885POLB 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.