Sugi Predict

Sugi Predict / Compounds / SCHEMBL358221

SCHEMBL358221

SCHEMBL358221

CCOC(=O)Cc1cccs1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 5/20 0.60
▸ MEN1 O00255 5/20 0.60
▸ KMT2A Q03164 5/20 0.60
▸ L3MBTL1 Q9Y468 4/20 0.60
▸ ESR2 Q92731 1/20 0.60
▸ ALDH1A1 P00352 3/20 0.56
▸ MAPT P10636 2/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ NPC1 O15118 4/20 0.56
▸ RAB9A P51151 3/20 0.56
▸ CYP1A2 P05177 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ HSD17B10 Q99714 3/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ HPGD P15428 2/20 0.52
▸ PKM P14618 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL29045225 0.97 POLB (0.57) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL28214977 0.93 MEN1 (0.54) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL28536342 0.87 POLB (0.50) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL6317907 0.87 POLB (0.55) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL9495408 0.86 NPC1 (0.58) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL9498848 0.83 ALDH1A1 (0.59) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL2398774 0.83 ALDH1A1 (0.59) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL1504839 0.83 ALDH1A1 (0.55) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL9495357 0.83 RAB9A (0.53) POLBMEN1KMT2AL3MBTL1ESR2
SCHEMBL9495815 0.82 ALDH1A1 (0.54) POLBMEN1KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292576-B Triphenylamine-based photo-thermal small molecule and preparation method and application thereof 山西大学 2023-05-30 — — CN claimed
CN-108276433-B Hydroboration method of ester 南京林业大学 2022-04-19 — — CN claimed
CN-105742709-A Lithium ion battery electrolyte and lithium ion battery using same 东莞市杉杉电池材料有限公司 2016-07-06 — — CN claimed
CN-105254650-A Synthesis method of antibacterial drug cefoxitin SICHUAN QINGSHANLVSHUI IND DEV CO LTD 2016-01-20 — — CN claimed
CN-103012437-A Method for preparing cefoxitin acid as antibacterial medicament SHANDONG XINQUAN PHARMACEUTICAL CO LTD 2013-04-03 — — CN claimed
CN-101007812-A Antibacterial drugs cefoxitin preparation process SHENZHEN SALUBRIS PHARMACEUTIC (CN) 2007-08-01 — — CN claimed
EP-3704117-B1 AZABICYCLO DERIVATIVES FOR TREATING OCULAR DISORDERS ALCON INC (CH) 2026-01-28 — — EP disclosed
US-20250367143-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA PHARM INC (US) 2025-12-04 — — US disclosed
US-20250367158-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA PHARM INC (US) 2025-12-04 — — US disclosed
US-12421249-B2 Inhibitors of APOL1 and methods of using same VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-09-23 — — US disclosed
US-20250171459-A1 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMA (US) 2025-05-29 — — US disclosed
EP-4548937-A1 ANTIBODY-DRUG COMPLEX Eisai R&D Management Co., Ltd. (JP) 2025-05-07 — — EP disclosed
EP-4543857-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 ACADIA Pharmaceuticals Inc. (US) 2025-04-30 — — EP disclosed
EP-0334119-A1 Compounds for inhibiting the biosynthesis of lipoxygenase-derived metabolites of arachidonic acid BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1989-09-27 — — EP disclosed
EP-0290280-A2 Anti-tumor platinum complexes, their preparation and their therapeutic use Sankyo Company Limited (JP) 1988-11-09 — — EP disclosed
EP-0267794-A2 Process for preparing polyolefins Nippon Petrochemicals Co., Ltd. (JP) 1988-05-18 — — EP disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 — — US disclosed
US-4107178-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1978-08-15 — — US disclosed
US-4086420-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-04-25 — — US disclosed
US-4051151-A Thiophene derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421249-B2 Inhibitors of APOL1 and methods of using same APOL1, PNLIP, APOB POLB 3247/4885MEN1 1732/4885KMT2A 4519/4885
US-20250367143-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 GPR88, GPR84, GPR68 POLB 3118/4885MEN1 4881/4885KMT2A 828/4885
US-20250171459-A1 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME APOL1, PDXK, PNLIP POLB 2514/4885MEN1 2743/4885KMT2A 3731/4885
US-20250367158-A1 MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 GPR88, GPR68, HTR2A POLB 3694/4885MEN1 4879/4885KMT2A 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.