SCHEMBL5562

SCHEMBL5562

Brc1ccc2[nH]ncc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 5/20 1.00
METAP2 P50579 2/20 1.00
CSNK2A1 P68400 1/20 1.00
DYRK1A Q13627 2/20 0.70
MAPT P10636 4/20 0.59
ROCK2 O75116 4/20 0.59
KDM4E B2RXH2 3/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
ROCK1 Q13464 3/20 0.59
ALDH1A1 P00352 2/20 0.59
GAA P10253 1/20 0.59
HPGD P15428 1/20 0.59
RAB9A P51151 1/20 0.59
HIF1A Q16665 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
CLK1 P49759 2/20 0.53
GSK3B P49841 2/20 0.53
CLK4 Q9HAZ1 2/20 0.53
DYRK3 O43781 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanate SCHEMBL27871749 0.89 NOS1 (0.79) NOS1METAP2CSNK2A1DYRK1AMAPT
SCHEMBL5902 0.83 NOS1 (1.00) NOS1METAP2CSNK2A1DYRK1AMAPT
SCHEMBL29364542 0.83 NOS1 (1.00) NOS1METAP2CSNK2A1DYRK1AMAPT
Tert-Butyl Formate SCHEMBL27690305 0.81 NOS1 (0.66) NOS1METAP2CSNK2A1DYRK1AMAPT
SCHEMBL27731429 0.79 NOS1 (0.62) NOS1METAP2CSNK2A1DYRK1AMAPT
SCHEMBL27708259 0.78 CSNK2A1 (0.60) NOS1METAP2CSNK2A1DYRK1AMAPT
Hydrazine SCHEMBL16698268 0.78 NOS1 (0.89) NOS1METAP2CSNK2A1DYRK1AMAPT
SCHEMBL13122080 0.74 ROCK2 (0.67) NOS1METAP2CSNK2A1DYRK1AROCK2
SCHEMBL277777 0.74 ROCK2 (0.59) NOS1METAP2CSNK2A1DYRK1AMAPT
SCHEMBL264176 0.74 NOS1 (1.00) NOS1METAP2CSNK2A1DYRK1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE Shanghai OuChem Bio-Technology Co., LTD (CN) 2026-04-23 US claimed
CN-119751424-A Novel method for synthesizing Bei Shude mol of methanesulfonic acid 重庆圣华曦药业股份有限公司 2025-04-04 CN claimed
WO-2023122498-A1 ONE-STEP OXIDE BATH FOR IMPROVING ADHESION OF POLYMERIC MATERIALS TO METAL SUBSTRATES MACDERMID, INCORPORATED (US) 2023-06-29 WO claimed
US-20230199972-A1 One-Step Oxide Bath for Improving Adhesion of Polymeric Materials to Metal Substrates MACDERMID, INCORPORATED 2023-06-22 US claimed
CN-114287437-A Atrazine topramezone dispersible suspending agent and preparation method and application thereof 山东德浩化学有限公司 2022-04-08 CN claimed
CN-111995577-A Synthetic method of 4-fluoro indazole 3-carbonitrile or derivatives thereof 上海代为化学科技有限公司 2020-11-27 CN claimed
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS DONG-A ST CO., LTD. (KR) 2026-05-28 US disclosed
CN-122010905-A Pyrazolyl derivatives as anticancer agents 诺华股份有限公司 2026-05-12 CN disclosed
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 US disclosed
US-20260124197-A1 NOVEL HETEROBICYCLIC COMPOUND FOR INHIBITING YAP-TEAD INTERACTION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME HANMI PHARMACEUTICAL CO LTD (KR) 2026-05-07 US disclosed
US-12612412-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE Shanghai OuChem Bio-Technology Co., LTD (CN) 2026-04-23 US disclosed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
WO-1997049698-A1 PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS GLAXO GROUP LIMITED (GB) 1997-12-31 WO disclosed
WO-1996041803-A1 PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION GLAXO GROUP LIMITED (GB) 1996-12-27 WO disclosed
EP-0137223-B1 PHOTOGRAPHIC IMAGE-RECEIVING ELEMENT FOR SILVER SALT DIFFUSION TRANSFER PROCESS FUJI PHOTO FILM CO., LTD. (JP) 1988-05-11 EP disclosed
US-4585725-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-04-29 US disclosed
EP-0137223-A2 Photographic image-receiving element for silver salt diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1985-04-17 EP disclosed
US-3963495-A Image-receiving element for silver salt diffusion transfer with layer of monoacrylates or monomethacrylates of polyhydric alcohols FUJI PHOTO FILM CO., LTD. (JA) 1976-06-15 US disclosed
US-3931220-A FUNGICIDE, BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124197-A1 NOVEL HETEROBICYCLIC COMPOUND FOR INHIBITING YAP-TEAD INTERACTION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME YAP1, RCC1, YES1 NOS1 2861/4885METAP2 4684/4885CSNK2A1 40/4885
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE NAT1, AADAC, NAA15 NOS1 496/4885METAP2 3620/4885CSNK2A1 930/4885
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS AXL, ERBB2, ERBB3 NOS1 1796/4885METAP2 2307/4885CSNK2A1 272/4885
US-12612412-B2 Antiviral heterocyclic compounds ZC3HAV1, NHERF1, HM13 NOS1 2373/4885METAP2 371/4885CSNK2A1 2167/4885
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 NOS1 2646/4885METAP2 3697/4885CSNK2A1 1660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.