Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CDA | P32320 | 1/20 | 0.45 |
| ▸ | PYGM | P11217 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711038 | 0.87 | TK2 (0.44) | PYGM | |
| SCHEMBL10699714 | 0.87 | MAPT (0.43) | LMNAMTORMAPTCDAPYGM | |
| SCHEMBL8911352 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TP53HTTBLMGMNN | |
| SCHEMBL31685622 | 0.83 | MAPT (0.51) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL16781797 | 0.83 | MAPT (0.51) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL7764746 | 0.83 | MAPT (0.51) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL5903974 | 0.82 | PYGM (0.49) | ALDH1A1TP53HTTBLMGMNN | |
| SCHEMBL7640658 | 0.82 | MAPT (0.47) | ALDH1A1TP53HTTBLMGMNN | |
| SCHEMBL635155 | 0.82 | MAPT (0.47) | ALDH1A1TP53HTTBLMGMNN | |
| SCHEMBL5903970 | 0.82 | PYGM (0.49) | ALDH1A1TP53HTTBLMGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262820-A1 | METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS | Universität Hamburg (DE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009121347-A1 | METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS | UNIVERSITÄT HAMBURG (DE) | 2009-10-08 | — | — | WO | disclosed |