Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906232 | 0.92 | ROCK2 (0.38) | ROCK2 | |
| SCHEMBL5906265 | 0.89 | NOTUM (0.48) | ARROCK2 | |
| SCHEMBL5906011 | 0.85 | ROCK2 (0.41) | ROCK2 | |
| SCHEMBL1829217 | 0.85 | PPARD (0.45) | ROCK2 | |
| SCHEMBL5906131 | 0.84 | AR (0.40) | ARROCK2RXRAGRIN1GRIN2B | |
| SCHEMBL5906188 | 0.83 | ROCK2 (0.48) | ROCK2 | |
| SCHEMBL1827020 | 0.83 | PPARG (0.39) | ROCK2 | |
| SCHEMBL5906276 | 0.82 | ALDH1A1 (0.37) | ARROCK2 | |
| SCHEMBL1829886 | 0.82 | PPARG (0.44) | — | |
| SCHEMBL5906397 | 0.82 | ROCK2 (0.45) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | CRYAA, PRXL2A, H1-2 | AR 3036/4885ROCK2 1976/4885RXRA 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.