Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5908617 | 0.91 | PRKD3 (0.35) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6498293 | 0.90 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL5908263 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6499194 | 0.81 | PIK3CA (0.34) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL5779740 | 0.68 | ADRB2 (0.42) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL5908463 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5908450 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5908454 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5780720 | 0.68 | KDM4E (0.37) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL5814129 | 0.67 | ADORA2A (0.35) | KDM4EALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056917-B2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20060106034-A1 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-18 | — | — | US | disclosed |
| US-20030092720-A1 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD (JP) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092720-A1 | Drug efflux pump inhibitor | ABCB11, ABCB1, ABCC1 | KDM4E 2648/4885ALDH1A1 1515/4885HPGD 811/4885 |
| US-20060106034-A1 | Drug efflux pump inhibitor | ABCB11, ABCB1, ABCC5 | KDM4E 2673/4885ALDH1A1 1244/4885HPGD 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.