SCHEMBL5909623

SCHEMBL5909623

CS(=O)(=O)c1n[c]c(Cl)cn1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
TLR9 Q9NR96 2/20 0.36
XBP1 P17861 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MITF O75030 1/20 0.31
S1PR4 O95977 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.31
PAX8 Q06710 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5909586 0.76 LMNA (0.31) NPC1ALDH1A1TP53MAPTHTT
SCHEMBL8427497 0.76 NPC1 (0.34) NPC1ALDH1A1TP53MAPTHTT
SCHEMBL5909707 0.73 NPC1 (0.32) NPC1ALDH1A1TP53MAPTHTT
SCHEMBL5909635 0.73 HTR6 (0.42) ALDH1A1MAPTHTTNPSR1HSD17B10
SCHEMBL5909582 0.72 ALDH1A1 (0.34) NPC1ALDH1A1TP53MAPTHTT
SCHEMBL1940334 0.72 TP53 (0.41) NPC1ALDH1A1TP53MAPTHTT
SCHEMBL8673102 0.67
SCHEMBL19204875 0.66
SCHEMBL5431831 0.65 CA12 (0.33) NPC1ALDH1A1TP53MAPTHTT
SCHEMBL11232326 0.65 LMNA (0.31) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060107869-A1 Inks for digital textile printing with reactive yellow fluorescent dyes DYSTAR TEXTILF DEUTSCHLAND KG (DE) 2006-05-25 US disclosed
US-6809187-B2 FIBER REACTIVE COPPER, COBALT OR CHROMIUM CHELATES; LIGHT-FASTNESS; EFFICIENT UNFIXED MATERIAL WASHOFF OYSTAR TEXTIL FARBEN GMBH & CO. (DE) 2004-10-26 US disclosed
US-20040054154-A1 Metal complex dyes based bucherered naphthols DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2004-03-18 US disclosed
US-6136970-A COLORFAST FIBER-REACTIVE DYES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed
US-6046311-A Water-soluble fiber-reactive dyes, preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2000-04-04 US disclosed
US-5938796-A Alkali system for dyeing cellulosic textiles by padding methods DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-08-17 US disclosed
US-5931975-A TRIAZINE REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US disclosed
US-5892006-A CONTAINING S-TRIAZINE RINGS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
US-5851239-A Spin dyeing process with dyeing salts DYSTAR TEXTILFARBEN GMBH & CO. (DE) 1998-12-22 US disclosed
US-5744589-A FOR DYEING OR PRINTING SUBSTRATES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
US-4659333-A Process for fixing dyes and prints with hot steam containing air CIBA-GEIGY CORPORATION (US) 1987-04-21 US disclosed
US-4652269-A Process for the continuous trichromatic dyeing of synthetic polyamide materials: including a blue anthraquinone reactive dye CIBA-GEIGY CORPORATION (US) 1987-03-24 US disclosed
US-4647285-A Process for printing cellulosic fibres with reactive dye and C3-18 aliphatic carboxylate salt fixing agent CIBA-GEIGY CORPORATION (US) 1987-03-03 US disclosed
US-4638054-A Aminonaphthol bisazo reactive dyes BAYER AKTIENGESELLSCHAFT (DE) 1987-01-20 US disclosed
US-4622396-A FIBER REACTIVE DYES BAYER AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed
US-4621138-A Triphendioxazine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1986-11-04 US disclosed
US-4591643-A Triphendioxazine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1986-05-27 US disclosed
US-4588411-A Long-shelflife print containing reactive dye and alkali acetate pastes and their use CIBA-GEIGY CORPORATION (US) 1986-05-13 US disclosed
US-4556707-A DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
US-4418015-A Phthalocyanine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060107869-A1 Inks for digital textile printing with reactive yellow fluorescent dyes IK, COL1A1, DDX41 NPC1 4150/4885ALDH1A1 568/4885TP53 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.