SCHEMBL591072

SCHEMBL591072

COc1ccc2cc(C(=O)ON3C(=O)CCC3=O)c(=O)oc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 7/20 0.63
▸ ALDH1A1 P00352 5/20 0.63
▸ HPGD P15428 4/20 0.63
▸ KDM4E B2RXH2 4/20 0.63
▸ GAA P10253 3/20 0.63
▸ GLA P06280 2/20 0.63
▸ CA12 O43570 1/20 0.63
▸ CA2 P00918 1/20 0.63
▸ CA3 P07451 1/20 0.63
▸ CA4 P22748 1/20 0.63
▸ CA6 P23280 1/20 0.63
▸ CA7 P43166 1/20 0.63
▸ CA9 Q16790 1/20 0.63
▸ CA14 Q9ULX7 1/20 0.63
▸ SLC16A3 O15427 1/20 0.63
▸ HSD17B10 Q99714 2/20 0.59
▸ RAB9A P51151 2/20 0.57
▸ NPC1 O15118 2/20 0.57
▸ POLB P06746 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL591197 0.84 MIF (0.60) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL30267413 0.84 MIF (0.60) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL6687148 0.82 MAOB (0.76) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL3363272 0.81 KDM4E (0.62) MAOBALDH1A1HPGDKDM4ECA12
SCHEMBL13823093 0.81 CA12 (0.53) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL23506385 0.81 MAOB (0.54) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL592979 0.80 MAOB (0.69) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL30790593 0.80 MAOB (0.69) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL1366230 0.79 ALDH1A1 (0.81) MAOBALDH1A1HPGDKDM4EGAA
SCHEMBL52650 0.79 ALDH1A1 (0.81) MAOBALDH1A1HPGDKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10254287-B2 Protein fluorescent nanoparticles and methods of synthesis thereof UNIVERSITY OF CONNECTICUT (US) 2019-04-09 — — US claimed
US-20170023580-A1 PROTEIN FLUORESCENT NANOPARTICLES AND METHODS OF SYNTHESIS THEREOF UNIVERSITY OF CONNECTICUT 2017-01-26 — — US claimed
US-12509435-B2 Compounds for selective binding to estrogen receptors alpha/beta relative to GPER/GPR30 and methods of treating disease states and conditions mediated through these receptors UNM RAINFOREST INNOVATIONS (US) 2025-12-30 — — US disclosed
US-20250067734-A1 Fluorescent Cellulose Particles ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-27 — — US disclosed
CN-118119848-A Fluorescent cellulose particles 旭化成株式会社 2024-05-31 — — CN disclosed
WO-2023089972-A1 FLUORESCENT CELLULOSE PARTICLES 旭化成株式会社 2023-05-25 — — WO disclosed
US-20230039502-A1 COMPOUNDS FOR SELECTIVE BINDING TO ESTROGEN RECEPTORS ALPHA/BETA RELATIVE TO GPER/GPR30 AND METHODS OF TREATING DISEASE STATES AND CONDITIONS MEDIATED THROUGH THESE RECEPTORS UNM RAINFOREST INNOVATIONS 2023-02-09 — — US disclosed
US-11150358-B2 Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry RIKEN (JP) 2021-10-19 — — US disclosed
EP-3314257-B1 CELL TRACKING REAGENTS AND THEIR METHODS OF USE LIFE TECHNOLOGIES CORP (US) 2021-06-16 — — EP disclosed
CN-108608703-B Polymer sheet 北欧化工公司 2021-03-16 — — CN disclosed
US-20200333474-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY RIKEN (JP) 2020-10-22 — — US disclosed
US-7018805-B2 α-Amylase assay and uses thereof VICAM L.P. (US) 2006-03-28 — — US disclosed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 — — EP disclosed
EP-1585971-A3 a-AMYLASE ASSAY AND USES THEREOF VICAM, L.P. (US) 2005-11-10 — — EP disclosed
EP-1585971-A2 a-AMYLASE ASSAY AND USES THEREOF VICAM, L.P. (US) 2005-10-19 — — EP disclosed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 — — WO disclosed
WO-2004020970-A2 α-AMYLASE ASSAY AND USES THEREOF VICAM, L.P. (US) 2004-03-11 — — WO disclosed
US-20040043116-A1 Alpha-amylase assay and uses thereof WATERS TECHNOLOGIES CORPORATION 2004-03-04 — — US disclosed
US-6362008-B1 Generic signalling mechanism for detection of analytes WATERS TECHNOLOGIES CORPORATION 2002-03-26 — — US disclosed
WO-1999032886-A1 GENERIC SIGNALLING MECHANISM FOR DETECTION OF ANALYTES VICAM, L.P. (US) 1999-07-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509435-B2 Compounds for selective binding to estrogen receptors alpha/beta relative to GPER/GPR30 and methods of treating disease states and conditions mediated through these receptors GPER1, ESR2, ESRRG MAOB 1131/4885ALDH1A1 2514/4885HPGD 2581/4885
US-20230039502-A1 COMPOUNDS FOR SELECTIVE BINDING TO ESTROGEN RECEPTORS ALPHA/BETA RELATIVE TO GPER/GPR30 AND METHODS OF TREATING DISEASE STATES AND CONDITIONS MEDIATED THROUGH THESE RECEPTORS GPER1, GPR35, GPR34 MAOB 1225/4885ALDH1A1 1983/4885HPGD 2381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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