Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499573 | 1.00 | ALDH1A1 (0.50) | ALDH1A1GPR35KDM4EMEN1GAA | |
| SCHEMBL17603289 | 0.78 | GPR35 (0.59) | ALDH1A1GPR35KDM4EMEN1GAA | |
| SCHEMBL9794635 | 0.77 | CTSB (0.46) | ALDH1A1GPR35KDM4EMEN1GAA | |
| SCHEMBL618153 | 0.75 | TDP1 (0.54) | ALDH1A1GPR35MEN1KMT2ATDP1 | |
| SCHEMBL621936 | 0.75 | GPR35 (0.56) | ALDH1A1GPR35KDM4EMAPTTDP1 | |
| SCHEMBL32691850 | 0.71 | GPR35 (0.64) | ALDH1A1GPR35MEN1MAPTKMT2A | |
| SCHEMBL14560963 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL16959740 | 0.71 | TDP1 (0.45) | ALDH1A1GPR35MAPTTDP1HPGD | |
| SCHEMBL1344484 | 0.71 | GPR35 (0.64) | ALDH1A1GPR35MEN1MAPTKMT2A | |
| SCHEMBL28027350 | 0.71 | TDP1 (0.73) | ALDH1A1GPR35KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12163968-B2 | Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers | BIO-RAD LABORATORIES, INC. (US) | 2024-12-10 | — | — | US | claimed |
| US-12163968-B2 | Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers | BIO-RAD LABORATORIES, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| EP-4208021-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | Bio-Rad Laboratories, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| CN-116097093-A | Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers | 生物辐射实验室股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022051443-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | BIO-RAD LABORATORIES, INC. (US) | 2022-03-10 | — | — | WO | disclosed |
| US-20220065878-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | BIO-RAD LABORATORIES, INC. | 2022-03-03 | — | — | US | disclosed |
| US-20210395487-A1 | COLORING COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2021-12-23 | — | — | US | disclosed |
| US-20180208775-A1 | NEW AROMATIC MACROCYCLIC METAL COMPLEX DYES AND THE SYNTHESIS THEREOF WITH ACTIVE NANO METAL POWDERS | OLGUN UGURSOY (TR) | 2018-07-26 | — | — | US | disclosed |
| EP-3157927-A1 | NEW AROMATIC MACROCYCLIC METAL COMPLEX DYES AND THE SYNTHESIS THEREOF WITH ACTIVE NANO METAL POWDERS | Olgun, Ugursoy (TR) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015199628-A1 | NEW AROMATIC MACROCYCLIC METAL COMPLEX DYES AND THE SYNTHESIS THEREOF WITH ACTIVE NANO METAL POWDERS | OLGUN UĞURSOY (TR) | 2015-12-30 | — | — | WO | disclosed |
| EP-2376908-B1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | BIO RAD LABORATORIES (US) | 2014-12-31 | — | — | EP | disclosed |
| US-8114580-B2 | Simulation of normal fresh blood platelets for reference control | BIO-RAD LABORATORIES, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| CN-102341701-A | Mimetics of normal fresh platelets | BIO RAD LABORATORIES | 2012-02-01 | — | — | CN | disclosed |
| EP-2376908-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | Bio-Rad Laboratories, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010083130-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | BIO-RAD LABORATORIES, INC. (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100178647-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | BIO-RAD LABORATORIES, INC. (US) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100178647-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | MPL, THPO, PFKP | ALDH1A1 4005/4885GPR35 2224/4885KDM4E 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.