Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407414 | 0.75 | NPC1 (0.50) | NPC1KDM4EPKMRAB9AALDH1A1 | |
| SCHEMBL2431912 | 0.73 | PKM (0.59) | NPC1KDM4EPKMRAB9AALDH1A1 | |
| SCHEMBL21711047 | 0.73 | TAS1R3 (0.73) | TAS1R3TAS1R1ALDH1A1HTT | |
| SCHEMBL64372 | 0.72 | PKM (0.55) | NPC1KDM4EPKMRAB9AALDH1A1 | |
| SCHEMBL1124336 | 0.71 | GPR119 (0.56) | NPC1KDM4EPKMRAB9AALDH1A1 | |
| SCHEMBL702662 | 0.71 | TAS1R3 (1.00) | TAS1R3TAS1R1ALDH1A1LMNAHTT | |
| SCHEMBL1010247 | 0.71 | PKM (0.59) | NPC1KDM4EPKMRAB9AALDH1A1 | |
| SCHEMBL13169591 | 0.71 | TAS1R3 (0.70) | TAS1R3TAS1R1NPC1RAB9AALDH1A1 | |
| SCHEMBL20878559 | 0.70 | TAS1R3 (0.69) | TAS1R3TAS1R1 | |
| SCHEMBL5094841 | 0.70 | GPR119 (0.52) | NPC1KDM4EPKMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |