Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622839 | 0.80 | POLB (0.46) | DPP4KMT2AMEN1TSHR | |
| SCHEMBL5924351 | 0.79 | CYP3A4 (0.66) | CYP3A4NFKB1PMP22ANPEPDPP4 | |
| SCHEMBL5924386 | 0.76 | SCN2A (0.57) | SCN2AKMT2AMEN1CA12CA1 | |
| SCHEMBL24195812 | 0.76 | HTT (0.49) | SCN2AKMT2AMEN1CA12CA1 | |
| SCHEMBL6794921 | 0.75 | MEN1 (0.46) | CYP3A4NFKB1PMP22ANPEPDPP4 | |
| SCHEMBL5391376 | 0.72 | SCN2A (0.43) | CYP3A4NFKB1PMP22ANPEPDPP4 | |
| SCHEMBL29654372 | 0.69 | CYP3A4 (0.40) | CYP3A4NFKB1PMP22SCN2AKMT2A | |
| SCHEMBL24525255 | 0.69 | CYP3A4 (0.40) | CYP3A4NFKB1PMP22SCN2AKMT2A | |
| SCHEMBL1974304 | 0.68 | KMT2A (0.64) | CYP3A4NFKB1PMP22SCN2AKMT2A | |
| SCHEMBL7751815 | 0.68 | MGLL (0.61) | CYP3A4NFKB1PMP22KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270628-A1 | Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2004101531-A1 | ANTIINFECTIVE 1,2,3-TRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270628-A1 | Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them | IL33, IL5, IL1B | CYP3A4 67/4885NFKB1 157/4885PMP22 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.