SCHEMBL5936627

SCHEMBL5936627

O=C([CH]c1cccc(Oc2ccccc2)c1)c1ccc(OCCN(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCHE P06276 13/20 0.50
ACHE P22303 12/20 0.50
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
EPOR P19235 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936595 0.92 KDM4E (0.51) BCHEACHEKDM4EMEN1ALDH1A1
SCHEMBL5936607 0.86 KDM4E (0.49) BCHEACHEKDM4EMEN1ALDH1A1
SCHEMBL5936618 0.83 NR4A2 (0.52) BCHEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL1122837 0.78 PPARG (0.51) KDM4EMEN1ALDH1A1KMT2AATM
SCHEMBL1123335 0.77 LPAR1 (0.52) ACHEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL1122838 0.76 PTGES (0.48) KDM4EMEN1ALDH1A1KMT2AATM
SCHEMBL1122672 0.76 PKM (0.63) BCHEACHEKDM4EMEN1KMT2A
SCHEMBL1123230 0.75 LPAR1 (0.48) MAOB
SCHEMBL27638146 0.75 PTGES (0.50) BCHEACHEKDM4EMEN1ALDH1A1
SCHEMBL1122692 0.75 LPAR1 (0.55) HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160894-A1 Benzamides as ppar modulators PPARD, PPARA, PPARG BCHE 520/4885ACHE 3017/4885KDM4E 2065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.