Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122837 | 0.86 | PPARG (0.51) | PTGESALOX5PPARGPPARALPAR1 | |
| SCHEMBL1123335 | 0.81 | LPAR1 (0.52) | PTGESALOX5PPARGPPARALPAR1 | |
| SCHEMBL1123189 | 0.80 | LPAR1 (0.51) | PPARGPPARALPAR1LPAR5KDM4E | |
| SCHEMBL1123277 | 0.79 | PPARG (0.49) | PTGESALOX5PPARGPPARALPAR1 | |
| SCHEMBL1122952 | 0.78 | LPAR1 (0.53) | LPAR1LPAR5FFAR1 | |
| SCHEMBL1123263 | 0.78 | ALOX5 (0.57) | PTGESALOX5NPC1RAB9AFFAR1 | |
| SCHEMBL1123230 | 0.77 | LPAR1 (0.48) | PTGESALOX5NPC1PPARGPPARA | |
| SCHEMBL27638146 | 0.77 | PTGES (0.50) | PTGESALOX5PPARGPPARALPAR1 | |
| SCHEMBL1122692 | 0.77 | LPAR1 (0.55) | PTGESALOX5PPARGPPARALPAR1 | |
| SCHEMBL5936627 | 0.76 | BCHE (0.50) | KDM4EMEN1ALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |