Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936960 | 0.75 | KDM4E (0.37) | ABCB1CYP3A4MAPK1KDM4EALDH1A1 | |
| SCHEMBL13109175 | 0.61 | ALDH1A1 (0.50) | CYP3A4MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL686849 | 0.60 | CYP1A2 (0.64) | CYP3A4ALDH1A1 | |
| SCHEMBL28226949 | 0.59 | CYP1A2 (0.42) | CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL1047550 | 0.58 | ABL1 (0.65) | CYP3A4MAPK1ALDH1A1HPGD | |
| SCHEMBL2028309 | 0.58 | ALDH1A1 (0.53) | CYP3A4MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL13564253 | 0.58 | ALDH1A1 (0.53) | CYP3A4MAPK1KDM4EALDH1A1HPGD | |
| Difucol Hexamethyl Ether SCHEMBL505203 | 0.57 | CYP1A2 (0.60) | CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL2093867 | 0.57 | MAPT (0.41) | MAPK1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31544423 | 0.57 | MGLL (0.50) | CYP3A4MAPK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156484-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156486-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156484-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
| US-20060156486-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156484-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, DSG1, JUP | ABCB1 3823/4885CYP3A4 799/4885MAPK1 1087/4885 |
| US-20060156486-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, DSG1, DSP | ABCB1 4074/4885CYP3A4 714/4885MAPK1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.