SCHEMBL5937656

SCHEMBL5937656

C=Cc1ccccc1N(c1ccc(C=Cc2ccc(C=Cc3ccc(N(c4ccccc4CC)c4ccccc4CC)cc3)cc2)cc1)c1ccccc1C=C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.37
RELA Q04206 2/20 0.37
CTDSP1 Q9GZU7 1/20 0.36
SNCA P37840 3/20 0.35
CHAT P28329 1/20 0.35
MEN1 O00255 4/20 0.33
MAPT P10636 4/20 0.33
KMT2A Q03164 4/20 0.33
NPC1 O15118 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
STAT3 P40763 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NSD2 O96028 1/20 0.32
POLB P06746 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5937678 0.90 FGF23 (0.41) APPRELACTDSP1SNCACHAT
SCHEMBL4400836 0.88 RELA (0.46) APPRELACTDSP1CHATMEN1
SCHEMBL5937717 0.87 NFE2L2 (0.38) APPRELACTDSP1CHATMAPT
SCHEMBL12640411 0.82 RELA (0.47) APPRELACTDSP1CHATMEN1
SCHEMBL14295898 0.81 CTDSP1 (0.41) APPRELACTDSP1CHATMEN1
SCHEMBL12763684 0.81 CTDSP1 (0.41) APPRELACTDSP1CHATMEN1
SCHEMBL4402188 0.80 FGF23 (0.47) APPRELACTDSP1SNCACHAT
SCHEMBL12640410 0.79 ALOX5 (0.41) APPRELACTDSP1CHATMEN1
SCHEMBL4400830 0.79 CTDSP1 (0.42) RELACTDSP1MEN1MAPTKMT2A
SCHEMBL12680419 0.77 C5AR1 (0.38) CTDSP1MEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed